Get a Quote

Aprepitant API | CAS 170729-80-3
CAS NO.: 170729-80-3
Chemical Formula: C23H21F7N4O3
Molecular Weight: 534.4270
DMF&GMP status: Please contact us for more details.
Description:
Aprepitant blocks the actions of chemicals in the body that trigger nausea and vomiting.

Aprepitant is used in adults and children to prevent nausea and vomiting caused by cancer chemotherapy. Aprepitant is also used (only in adults) to prevent nausea and vomiting that may be caused by surgery.

Aprepitant is given ahead of time and will not treat nausea or vomiting that you already have.

Aprepitant capsules are for use in adults and children who are at least 12 years old. Aprepitant oral suspension (liquid) can be given to adults and children as young as 6 months old.
Approvals
Active Ingredient Dosage Form; Route Strength Proprietary Name Applicant
APREPITANTCAPSULE; ORAL125MGAPREPITANTSANDOZ
APREPITANT CAPSULE; ORAL 40MG APREPITANT SANDOZ
APREPITANT CAPSULE; ORAL 80MG APREPITANT SANDOZ
APREPITANT CAPSULE; ORAL 125MG EMEND MERCK
APREPITANT CAPSULE; ORAL 40MG EMEND MERCK
APREPITANT CAPSULE; ORAL 80MG EMEND MERCK
APREPITANT FOR SUSPENSION; ORAL 125MG/KIT EMEND MSD MERCK CO
FOSAPREPITANT DIMEGLUMINE POWDER; INTRAVENOUS EQ 150MG BASE/VIAL EMEND MERCK AND CO INC
Patent Data
Patent No. Patent Expiration Drug Substance Claim Drug Product Claim Patent Use Code
60967421-Jul-18YYU - 745
6096742 1-Jul-18 Y Y U - 1744
6096742 1-Jul-18 Y Y U - 1743
8258132 26-Sep-27 Y U - 901
8258132 26-Sep-27 Y U - 1743
5691336 Mar -4- 2019 Y Y
Exclusive Data
Exclusivity Code Exclusivity Expiration
NPP Aug-28- 2018
D-155 Feb-1-2019