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TRIFAROTENE
CAS NO.: 895542-09-3
Chemical Formula: C29H33NO4
Molecular Weight: 459.6000
DMF&GMP status: Please contact us for more details.
Description:
Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to [vitamin A], though later generation retinoids such as trifarotene and [adapalene] bear little structural resemblance to vitamin A and are analogous only in function. Trifarotene is considered the first of the "fourth-generation" retinoids due to its uniquely selective activity - this selectivity appears to confer improved efficacy and reduced side effects as compared to older, less selective retinoids.

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Approvals
Active Ingredient Dosage Form; Route Strength Proprietary Name Applicant
TRIFAROTENECREAM;TOPICAL0.005%AKLIEFGALDERMA LABORATORIES LP
Patent Data
Patent No. Patent Expiration Drug Substance Claim Drug Product Claim Patent Use Code
780770810/01/2026DSDP
822750712/21/2025U-818
847087112/21/2025U-2639
908477805/30/2033DPU-134
Exclusive Data
Exclusivity Code Exclusivity Expiration
NCE 10/04/2024