Get a Quote

Dexmedetomidine Hydrochloride, Injection
CAS NO.: 145108-58-3
Chemical Formula: C13H17ClN2
Molecular Weight: 236.7400
DMF&GMP status: Please contact us for more details.
Description:
Mechanism of Action
Dexmedetomidine hydrochloride in 0.9% sodium chloride injection is a relatively selective alpha2-adrenergic agonist with sedative properties. Alpha2 selectivity is observed in animals following slow intravenous infusion of low and medium doses (10 to 300 mcg/kg). Both alpha1 and alpha2 activity is observed following slow intravenous infusion of high doses (≥1,000 mcg/kg) or with rapid intravenous administration.

Dexmedetomidine Hydrochloride is the hydrochloride salt form of dexmedetomidine, an imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic and sedative activities. Dexmedetomidine selectively binds to and activates presynaptic alpha-2 adrenoceptors located in the brain, thereby inhibiting the release of norepinephrine from synaptic vesicles. This leads to an inhibition of postsynaptic activation of adrenoceptors, which inhibits sympathetic activity, thereby leading to analgesia, sedation and anxiolysis.

**Please noted, we do not sell medicines to Individuals. Our products are for Pharmaceutical Companies, Wholesalers, Research Organization and Institutes. A safe online Medicine store should have License by the state board of pharmacy, have a licensed pharmacist, require a prescription and more. For instructions about how to purchase the medicines online, please review FDA official website.
Approvals
Active Ingredient Dosage Form; Route Strength Proprietary Name Applicant
DEXMEDETOMIDINE HYDROCHLORIDEINJECTABLE;INJECTIONPlease contact us for more detailsPlease contact us for more detailsPlease contact us for more details
Patent Data
Patent No. Patent Expiration Drug Substance Claim Drug Product Claim Patent Use Code
N.A.N.A.N.A.N.A.N.A.
Exclusive Data
Exclusivity Code Exclusivity Expiration
N.A. N.A.