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Relebactam
CAS NO.: 1174018-99-5
Chemical Formula: C12H20N4O6S
Molecular Weight: 348.3800
DMF&GMP status: Please contact us for more details.
Description:
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam]. It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes [imipenem] and [cilastatin] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal infections in adults. It is considered to be a last-line treatment option and gained FDA approval as part of the combination product RecarbrioⓇ in July 2019.

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Approvals
Active Ingredient Dosage Form; Route Strength Proprietary Name Applicant
CILASTATIN SODIUM; IMIPENEM; RELEBACTAMPOWDER;INTRAVENOUSEQ 500MG BASE/VIAL; 500MG/VIAL; 250MG/VIALRECARBRIOMERCK SHARP AND DOHME CORP A SUB OF MERCK AND CO INC
Patent Data
Patent No. Patent Expiration Drug Substance Claim Drug Product Claim Patent Use Code
848709311/19/2029DSDPU-2586 U-2587 U-2840
Exclusive Data
Exclusivity Code Exclusivity Expiration
N.A. N.A.