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Thiotepa, Injection
CAS NO.: 52-24-4
Chemical Formula: C6H12N3PS
Molecular Weight: 189.2200
DMF&GMP status: Please contact us for more details.
Description:
Mechanism of Action
Thiotepa is a cytotoxic agent of the polyfunctional type, related chemically and pharmacologically to the nitrogen mustard. The radiomimetic action of thiotepa is believed to occur through the release of ethyleneimine radicals which, like irradiation, disrupt the bonds of DNA. One of the principle bond disruptions is initiated by alkylation of guanine at the N-7 position, which severs the linkage between the purine base and the sugar and liberates alkylated guanines.

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Approvals
Active Ingredient Dosage Form; Route Strength Proprietary Name Applicant
THIOTEPAINJECTABLE;INJECTIONPlease contact us for more detailsPlease contact us for more detailsPlease contact us for more details
Patent Data
Patent No. Patent Expiration Drug Substance Claim Drug Product Claim Patent Use Code
N.A.N.A.N.A.N.A.N.A.
Exclusive Data
Exclusivity Code Exclusivity Expiration
N.A. N.A.